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標題Title: The measurements of ultrasound parameters on calcaneus by two-sided interrogation techniques
作者Authors: 陳培展,Tainsong Chen..等
上傳單位Department: 電機工程系
上傳時間Date: 2009-11-18
上傳者Author: 陳培展
審核單位Department: 電機工程系
審核老師Teacher: 陳培展
檔案類型Categories: 論文Thesis
關鍵詞Keyword: quantitative ultrasound (QUS), calcaneus, two-sided, interrogation techniques, osteoporosis, ultrasound densitometer
摘要Abstract: Recently, ultrasound techniques have become an important alternative in the
assessment of osteoporosis. The speed of sound (SOS) and broadband
ultrasound attenuation (BUA) on calcaneus are commonly used in
ultrasound densitometer for osteoporosis evaluation. However, the
quantitative ultrasound (QUS) parameters provided by densitometer using
most commercial ultrasound instruments are based on the assumption of a
fixed bone thickness. Information on bone thickness is a critical factor for
accurate estimation of SOS through conventional approaches; yet, the
thickness of bone tissue is not available through in vivo measurements and it
is almost impossible to obtain the thickness of bone tissue via conventional
approaches. Therefore, the SOS measurements will be incorrect. The
purpose of this work is to develop a two-sided interrogation technique for
the SOS measurements that is less susceptible to bone thickness. The results
show that this proposed technique can obtain a better SOS estimation on
bone tissue. Using bone phantoms that mimic actual tissue, the validity of
the approach is confirmed with measurement showing high accuracy
(>99%) and low standard deviation (<0.5%). Finally, the measurements of
14 healthy subjects are also reported. The results show that this technique
can provide the bone thickness information to reduce the SOS estimation
errors compared with the fixed bone thickness assumption.
Keywords: quantitative ultrasound (QUS), calcaneus, two-sided

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